임플란트 표면특성에 따른 단백질의 흡착
Effect of implant surface characteristics on protein adsorption: a literature review
박지선, 임영준,
소속 상세정보
박지선 ( Park Ji-Sun ) - 서울대학교 치의학대학원 치의학과
임영준 ( Lim Young-Jun ) - 서울대학교 치의학대학원 치과보철학교실
KMID : 1034220120040020005
Abstract
Along with advances in implant technology and surgical techniques, the interaction between implant materials and the surrounding biological tissues has become of great interest for achieving optimal osseointegration. Protein adsorption to the implant surface, in particular, is the first biological reaction that triggers the cascade of events of osseointegration upon implant placement. The adsorped protein layer mediates cell adhesion to implant biomaterials, which ultimately determines biocompatibility of the implants. As a result, this process is affected by implant surface properties such as wettability, roughness, surface charge, and chemical composition. This review discusses current knowledge of the effect of implant surface characteristics on protein adsorption in the context of the physical and chemical properties of the implant surface.
키워드
dental implant; protein adsorption; surface characterization; wettabil
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